"Glutathione" is a three-peptide molecule found in the bodies of mammals and is a substance secreted by the liver, where it removes the toxicity of harmful compounds so that they can be disposed of by the bile, and some of the glutathione is released from the liver directly into the bloodstream, as it helps to maintain the integrity of cells Red blood, and the protection of white blood cells, as there is also glutathione in the lungs and intestinal tract, and as the human gets older, levels of glutathione decrease. It is an antioxidant that plays an important role in preventing oxidative damage to the skin. In addition to many recognized biological functions, glutathione is associated with the ability to lighten the complexion.
Glutathione is a ingredient in some cosmetics and is used to whiten the skin. It is also available in the form of a cream, soap, lotion, nasal spray, and injection. The glutathione skin cells used on the skin do not effectively absorb lotion as the thiol group undergoes a rapid formation of disulfide. When taken orally, glutathione is degraded by digestive enzymes, which leads to reduced bio availability. The glutathione level increases in small amounts temporarily when given in large oral doses.
As a result, the effectiveness of glutathione, which is externally administered, slows down due to its inability to cross cell membranes efficiently and its rapid degradation by enzymes in the digestive system. Conversely, intravenous glutathione delivers very high doses directly into the circulatory system and this is the preferred method for administering glutathione. However, this method of administering antioxidant may inundate cells with glutathione and this may cause reduction in stress, which may expose people to the potential health risks associated with long-term use of high doses of glutathione.
Glutathione can be combined with many other factors such as vitamin C to increase its absorption, and with N-acetyl cysteine to measure its level, and with other antioxidants such as vitamin E. Of skin-lightening factors such as (hydroquinone) ٫ which is carcinogenic, and (monobenzone) that causes depigmentation Irreversible (irreversible).
-What are the benefits of "glutathione" on various parts of the body?
Glutathione not only protects individual cells, but also protects the arterial tissue, brain, heart, immune system cells, kidneys, lens of the eyes, liver, lungs, and skin from destruction, due to oxidation, which plays an important role in preventing cancer, especially liver cancer and may have an anti-aging effect.
What are the natural sources of glutathione?
Glutathione is present in fruits and vegetables, especially grapes, carrots, oranges, grapefruit, avocados, broccoli in all its colors, garlic, tomatoes, spinach, fresh and dried turmeric, watermelon, potatoes and sweet potatoes in all their colors and types, zucchini and others, and it is best to eat glutathione by foods Natural, and not in the form of nutritional supplements, and for this we find that natural foods alone purify and cleanse the liver, blood and body, and help to unify the color and homogeneity of the skin, and naturally beautify it.
-What are the medical uses of glutathione?
Glutathione is one of the most popular antioxidants and for this it is mainly used for cancer patients as a kind of supporting the body and strengthening its immunity by helping it to oxidize food. Glutathione is also used in the treatment of Parkinson's disease, liver and breast cancer and low blood pressure.
Skin bleaching is one of the side effects of glutathione, and the beginning of the idea of using it in brightening was when observing that cancer patients and users of these capsules have more freshness and lighter skin than before, so they started using antioxidants to obtain white skin, and it is necessary to obtain quantities A large amount of glutathione on a daily basis until its side effects appear as skin lightening.
Glutathione pills benefits for the skin:
One of the things that concern many women most is the obtaining of bright white skin full of freshness and vitality, so always looking for all that is new and effective in the field of skin-lightening, and glutathione needles and pills are among the means that started the discussion on its effectiveness and the degree of its safety as it occupied the centers The first in materials that lighten the skin.
Specialists have noted that individuals who accept the use of glutathione have become more whitening and glowing, and research and study have proven that glutathione stops the activity of melanin in the body and thus contributes to whitening the skin,
Hence it was used in the manufacture of skin-lightening preparations, and its concentration in these products was definitely increased to 1500 mg, and here also the controversy arose over the degree of safety of this high percentage.
The high concentration levels specifically in the lightening needles are intended to obtain effective and strong effect and fast, but so far it has not been confirmed that they have a degree of safety, so care must be taken of glutathione products that are not subject to examination and licenses of the Ministry of Health.
In spite of this, many women are obsessed with lightening, causing them to accept glutathione pills and glutathione creams, as they are promoted by some greedy manufacturers of these substances because they are made in high concentrations and marketed in a way that attracts customers.
It promotes the idea that a high percentage is the most effective and that a high dose will make your skin lighter and more beautiful in a short period without regard to the adverse effects that can occur.Adverse effects of using glutathione pills at high concentrations
Kidney function disorders may lead to kidney failure.Deficiency in the functions of the gland resulting in the problem of hair loss, and other accompanying health problems.
Acute skin infections.
Are glutathione pills among the FDA approved medicines?
It is a natural substance so it is monitored by the Food and Drug Authority, but approval for its circulation is not required and this means that it is a safe product that is used after the approval of the doctors of internal medicine, nutrition, brain, internal nerves, and liver, but with appropriate concentrations of disease states.
PLEASE use glutathione pills with appropriate portions and without overeating. You can take lean servings at a concentration of 500 mg to 750 mg. You can take a daily ration of up to three tablets per day, equal to 1500 mg. In this case it is used as a nutritional supplement of fortified vitamins, as it is characterized by its ability to lighten more. Of the creams, as they act on the skin of the body in general, they include correcting the skin tone as a whole, but the glutathione creams have very poor absorption.
The effect of glutathione pills on breastfeeding. Certainly most of the supplements and medications that the mother takes during the period of breastfeeding, of which varying proportions reach the fetus through milk, which is reflected on the infant in one way or another, so please read the internal leaflet of drugs before getting to know to know the degree of their effect on breastfeeding, but it is desirable to stop Take them during this time, to avoid any side effects that may harm the infant.
Ways to Increase Intracellular Glutathione:
Considering how important glutathione is to health, many researchers have looked for ways to increase intracellular and intramitochondrial levels. The good news is that there are several effective strategies. The first, of course, is to decrease the need for glutathione, which means decreasing toxic load. The most obvious is limiting alcohol consumption, Less obvious is decreasing exposure to POPs, the primary source of which are conventionally grown foods.
Another strategy is to provide other antioxidants to decrease oxidative stress. A good example is α-lipoic acid, supplementation of which increases mitochondrial glutathione levels.
Summary:
Clearly, adequate availability of glutathione is critical for maintaining health, protecting the body from toxins, and promoting longevity. Fortunately, there is much we can do to optimize glutathione levels: primarily decrease toxin exposure (including alcohol) and promote production with regular consumption of whey or Acetylcysteine.
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